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CASE STUDIES The remainder of this chapter will deal with case studies where pharmaco- kineticpharmacodynamic models established preclinically were used to help guide clinical development or answer strateby development questions that could not be addressed in humans. 54 II 1305. Fatty acids can be sat- urated or unsaturated.35, 51.
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Advantages and Limitations of Diagrams Although the zones of corrosion, immunity and passivity are clearly of fundamental importance in corrosion science it must be emphasised again that they have serious limitations in the solution of practical problems, and can lead to unfortunate misconceptions unless they are interpreted with caution.
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© 2002 ECV · Editio Cantor Verlag Aulendorf (Germany) Metabolism 141 ISOZYMES. Such lactones are potentially useful synthons for a number of natural products (37).
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